A central IRB consolidates ethical review for a multi-site study under one board, reducing duplication and inconsistency. Central and single IRB are overlapping concepts; sIRB is the federal term used by NIH and the Common Rule, while cIRB is more common in industry contexts.
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Glossary Term
Central IRB (cIRB)
Governance
Also known as: cIRB, central institutional review board
An IRB serving multiple unaffiliated sites or sponsors as a single review body, often used in industry-sponsored research.
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